Peptide Atlas · Mineral

Sodium chloride (injectable carrier/electrolyte)

In the BaSICS trial of 10,520 critically ill patients, a balanced solution did not lower 90-day mortality compared with 0.9% sodium chloride (26.4% against 27.2%).

established

provisional
PubChem 5234
2 citations
0 discussions
0 followers
WFI-NaCl
normal saline (0.9%)
physiological saline

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Sodium chloride (injectable carrier/electrolyte). Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Balanced solution versus 0.9% saline: no difference in 90-day mortality (BaSICS RCT)	established	pmid 34375394
Balanced crystalloids versus saline in ICU patients (BEST-Living IPD meta-analysis)	established	pmid 38043564

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.