L-alanyl-L-glutamine is a dipeptide used to deliver glutamine in intravenous nutrition; after major abdominal surgery, parenteral nutrition enriched with it improved nitrogen balance and lymphocyte recovery in a randomized, double-blind study of 28 patients.
emerging — human data exists, and it is thin or contested
every claim resolves to its source
All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.
Summary
L-alanyl-L-glutamine is a dipeptide used to deliver glutamine in intravenous nutrition; after major abdominal surgery, parenteral nutrition enriched with it improved nitrogen balance and lymphocyte recovery in a randomized, double-blind study of 28 patients. · pmid:9488531
In a French multicenter double-blind trial in 114 intensive-care patients, alanyl-glutamine-supplemented parenteral nutrition lowered complicated outcomes (41% against 61%), mainly infections and pneumonia, and hyperglycemia, without changing early deaths or 6-month survival. · pmid:16505644
Proportion of the 2 claims about Alanyl-Glutamine (Dipeptiven) standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.
Living evidence history
2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.
Structure
No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Alanyl-Glutamine (Dipeptiven) yet.
Dose evidence, rung by rung
No established safe human dose. Nothing on file establishes one. That is a statement about the evidence PepJunkie holds, not a promise about the molecule.
Approved-label dose· a resolved regulatory document names a labelled dose
nothing resolved on this rung
Studied human doses· resolved human studies at the established tier
nothing resolved on this rung
Observational evidence· resolved human data at the emerging tier: thin, or contested
L-alanyl-L-glutamine dipeptide-supplemented total parenteral nutrition reduces infectious complications and glucose intolerance in critically ill patients: the French controlled, randomized, double-blind, multicenter study. · pmid 16505644 · 2006
Total parenteral nutrition with glutamine dipeptide after major abdominal surgery: a randomized, double-blind, controlled study. · pmid 9488531 · 1998
Community-reported protocols· protocol propositions from distinct members, counted once per human
nothing resolved on this rung
Preclinical evidence· resolved animal, cell or mechanistic work
nothing resolved on this rung
2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.
Negative findings
failure is information
Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.