preclinical — animal, cell or mechanistic work — not yet about people
every claim resolves to its source
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created page created as 'AOD-9604' with aliases Anti-Obesity Drug 9604, hGH Fragment 177-191 modified, Tyr-hGH frag 176-191 · 2026-09-27 04:00 · somebody
kind set kind set to peptide: palette r1 · 2026-09-27 04:00 · somebody
fact added identity: CAS registry number 221231-10-3. · 2026-09-27 04:00 · somebody
fact added summary: AOD9604 is a synthetic analogue of the lipolytic domain of human growth hormone, taken from the hormone's C-terminus. · 2026-09-27 04:00 · somebody
fact added history: In obese Zucker rats, 19 days of oral AOD9604 cut body weight gain by more than half, and unlike intact growth hormone i · 2026-09-27 04:00 · somebody
fact added mechanism: In mice its lipolytic action was not mediated directly through the beta-3 adrenergic receptor, although it raised that r · 2026-09-27 04:00 · somebody
citation added pmid 11146367 cited as preclinical: Oral AOD9604 reduced weight gain in obese Zucker rats without impairing insulin sensitivity · 2026-09-27 04:00 · somebody
citation added pmid 11713213 cited as preclinical: Lipolytic action of hGH and AOD9604 in obese and beta-3 receptor knock-out mice · 2026-09-27 04:00 · somebody
Negative findings
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