Peptide Atlas · Buffer system

Bicarbonate buffer

A pH 6.8 bicarbonate buffer resembling the ionic composition and buffer capacity of intestinal fluid was developed as a more physiological dissolution medium than phosphate buffer.

preclinical

provisional
1 citation
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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

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- preclinical
  Claim: Physiological bicarbonate buffer for dissolution testing standing
- resolved
Evolution of a physiological pH 6.8 bicarbonate buffer system: application to the dissolution testing of enteric coated products.
Liu F, Merchant HA, Kulkarni RP, Alkademi M, Basit AW
pmid 21255647

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