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Cagrilintide

Cagrilintide is a long-acting analogue of amylin, a pancreatic hormone that induces satiety; in a 26-week phase 2 trial in 706 adults with overweight or obesity, once-weekly doses reduced body weight by 6.0% to 10.8% against 3.0% on placebo, with more nausea.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

No trial registration is cited for it. A registered trial cites as an NCT number and resolves through ClinicalTrials.gov.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.