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Cerebrolysin

Cerebrolysin is a neuropeptide preparation described as mimicking the action of endogenous neurotrophic factors on brain protection and repair; it is a preparation, not a single molecule.

What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 3 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

    • emerging
      Claim: CARS randomized placebo-controlled trial of motor recovery after stroke standing
    • resolved

    Cerebrolysin and Recovery After Stroke (CARS): A Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial.

    Muresanu DF, Heiss WD, Hoemberg V, Bajenaru O, Popescu CD, Vester JC, Rahlfs VW, Doppler E, Meier D, Moessler H, Guekht A

    pmid 26564102

    • emerging
      Claim: Meta-analysis of nine randomized trials in early post-stroke recovery standing
    • resolved

    Safety and efficacy of Cerebrolysin in early post-stroke recovery: a meta-analysis of nine randomized clinical trials.

    Bornstein NM, Guekht A, Vester J, Heiss WD, Gusev E, Hömberg V, Rahlfs VW, Bajenaru O, Popescu BO, Muresanu D

    pmid 29248999

    • preclinical
      Claim: Review of neurotrophic pharmacology in dementia and stroke models standing
    • resolved

    The pharmacology of neurotrophic treatment with Cerebrolysin: brain protection and repair to counteract pathologies of acute and chronic neurological disorders.

    Masliah E, Díez-Tejedor E

    pmid 22514792

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.