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Peptide Atlas · Mineral

Chromic chloride hexahydrate

In a woman on total parenteral nutrition for over five years, glucose intolerance, weight loss and peripheral neuropathy developed with very low blood chromium, and all were reversed by adding chromium to the infusion.

What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Summary

In a woman on total parenteral nutrition for over five years, glucose intolerance, weight loss and peripheral neuropathy developed with very low blood chromium, and all were reversed by adding chromium to the infusion. · pmid:192066

A second patient on long-term parenteral nutrition developed severe glucose intolerance and confusion that chromium supplementation reversed, supporting chromium deficiency as a complication of long-term intravenous feeding. · pmid:104057

Identity

PubChem CID 104957: Chromic chloride hexahydrate, Cl3CrH12O6, 266.44 g/mol. · pubchem:104957

IUPAC name: trichlorochromium;hexahydrate. · pubchem:104957


Where the evidence actually sits

Emerging100%

Proportion of the 2 claims about Chromic chloride hexahydrate standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.


Living evidence history

Chromium deficiency, glucose intolerance, and neuropathy reversed by chromium supplementation, in a patient receiving long-term total parenteral nutrition. (1977) · emergingChromium deficiency during total parenteral nutrition. (1979) · emerging19771979

2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.


Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Chromic chloride hexahydrate yet.


Dose evidence, rung by rung

No established safe human dose. Nothing on file establishes one. That is a statement about the evidence PepJunkie holds, not a promise about the molecule.

  1. Approved-label dose · a resolved regulatory document names a labelled dose

    nothing resolved on this rung

  2. Studied human doses · resolved human studies at the established tier

    nothing resolved on this rung

  3. Observational evidence · resolved human data at the emerging tier: thin, or contested
    • Chromium deficiency during total parenteral nutrition. · pmid 104057 · 1979
    • Chromium deficiency, glucose intolerance, and neuropathy reversed by chromium supplementation, in a patient receiving long-term total parenteral nutrition. · pmid 192066 · 1977
  4. Community-reported protocols · protocol propositions from distinct members, counted once per human

    nothing resolved on this rung

  5. Preclinical evidence · resolved animal, cell or mechanistic work

    nothing resolved on this rung

2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.