Using deuterium-labelled forms, natural (RRR) vitamin E reached about twice the plasma and tissue availability of synthetic (all-rac) vitamin E in humans.
established — replicated in humans, or settled by a regulator
every claim resolves to its source
All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.
Summary
Using deuterium-labelled forms, natural (RRR) vitamin E reached about twice the plasma and tissue availability of synthetic (all-rac) vitamin E in humans. · pmid:9537614
In a three-year randomized trial in healthy adults with raised LDL cholesterol, DL-alpha-tocopherol (400 IU a day) reduced LDL oxidation but did not slow carotid artery wall thickening. · pmid:12234947
Proportion of the 2 claims about DL-alpha-Tocopherol (free Vitamin E) standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.
Living evidence history
2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.
Structure
No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for DL-alpha-Tocopherol (free Vitamin E) yet.
Dose evidence, rung by rung
A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.
Approved-label dose· a resolved regulatory document names a labelled dose
nothing resolved on this rung
Studied human doses· resolved human studies at the established tier
Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS). · pmid 12234947 · 2002
Observational evidence· resolved human data at the emerging tier: thin, or contested
Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E. · pmid 9537614 · 1998
Community-reported protocols· protocol propositions from distinct members, counted once per human
nothing resolved on this rung
Preclinical evidence· resolved animal, cell or mechanistic work
nothing resolved on this rung
2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.
Negative findings
failure is information
Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.