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Peptide Atlas · Vitamin

DL-alpha-Tocopheryl acetate (Vitamin E acetate)

In the Finnish Alpha-Tocopherol, Beta-Carotene trial of 29,133 male smokers, 50 mg a day of alpha-tocopherol for about six years was followed by 32% fewer prostate cancers than without it.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Summary

In the Finnish Alpha-Tocopherol, Beta-Carotene trial of 29,133 male smokers, 50 mg a day of alpha-tocopherol for about six years was followed by 32% fewer prostate cancers than without it. · pmid:9521168

When vaped, vitamin E acetate was found in lung fluid from 48 of 51 patients with e-cigarette or vaping product use-associated lung injury (EVALI) and in none of the healthy comparators. · pmid:31860793

Identity

PubChem CID 2117: Dl-alpha-tocopherol acetate, C31H52O3, 472.7 g/mol. · pubchem:2117

CAS registry number 7695-91-2. · pubchem:2117

IUPAC name: [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl] acetate. · pubchem:2117


Where the evidence actually sits

Established50%
Emerging50%

Proportion of the 2 claims about DL-alpha-Tocopheryl acetate (Vitamin E acetate) standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.


Living evidence history

Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: incidence and mortality in a controlled trial. (1998) · emergingVitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI. (2020) · established19982020

2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.


Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for DL-alpha-Tocopheryl acetate (Vitamin E acetate) yet.


Dose evidence, rung by rung

A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.

  1. Approved-label dose · a resolved regulatory document names a labelled dose

    nothing resolved on this rung

  2. Studied human doses · resolved human studies at the established tier
    • Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI. · pmid 31860793 · 2020
  3. Observational evidence · resolved human data at the emerging tier: thin, or contested
    • Prostate cancer and supplementation with alpha-tocopherol and beta-carotene: incidence and mortality in a controlled trial. · pmid 9521168 · 1998
  4. Community-reported protocols · protocol propositions from distinct members, counted once per human

    nothing resolved on this rung

  5. Preclinical evidence · resolved animal, cell or mechanistic work

    nothing resolved on this rung

2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.