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Peptide Atlas · Vitamin

Folic acid

In a public-health programme in China covering about 248,000 pregnancies, 400 micrograms of folic acid a day around conception cut neural-tube defects by up to 85% in the northern high-risk region.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Folic acid. Tier reflects study design, not enthusiasm.
ClaimTierSource
Periconceptional folic acid prevented neural-tube defects in Chinaestablishedpmid 10559448
Folic acid fortification reduced neural-tube defects by 46% in Canadaestablishedpmid 17625125

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.