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Peptide Atlas · Peptide

HGH Fragment 176-191

Human growth hormone's fat-mobilising activity has been studied through synthetic fragments of its C-terminus, the region fragment 176-191 spans.

What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

Summary

Human growth hormone's fat-mobilising activity has been studied through synthetic fragments of its C-terminus, the region fragment 176-191 spans. · pmid:11713213

History

Both intact human growth hormone and its C-terminal lipolytic fragment AOD9604 reduced body weight and body fat in obese mice over 14 days of treatment. · pmid:11713213

Identity

PubChem CID 16131230: Somatotropin (176-191), C78H123N23O22S2, 1799.1 g/mol. · pubchem:16131230

CAS registry number 66004-57-7. · pubchem:16131230


Where the evidence actually sits

Preclinical only100%

Proportion of the 1 claim about HGH Fragment 176-191 standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.


Living evidence history

The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. (2001) · preclinical20012001

1 resolved citation, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.


Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for HGH Fragment 176-191 yet.


Dose evidence, rung by rung

No established safe human dose. Nothing on file establishes one. That is a statement about the evidence PepJunkie holds, not a promise about the molecule.

  1. Approved-label dose · a resolved regulatory document names a labelled dose

    nothing resolved on this rung

  2. Studied human doses · resolved human studies at the established tier

    nothing resolved on this rung

  3. Observational evidence · resolved human data at the emerging tier: thin, or contested

    nothing resolved on this rung

  4. Community-reported protocols · protocol propositions from distinct members, counted once per human

    nothing resolved on this rung

  5. Preclinical evidence · resolved animal, cell or mechanistic work
    • The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice. · pmid 11713213 · 2001

1 resolved citation, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.