Peptide Atlas · Protein

Human Chorionic Gonadotropin (hCG)

Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein hormone; in its crystal structure each of its two subunits folds around a cystine knot, and a segment of the beta subunit wraps around the alpha subunit like a seat belt.

emerging

provisional
2 citations
0 discussions
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Novarel
Pregnyl
choriogonadotropin alfa (recombinant, Ovidrel/Ovitrelle)
chorionic gonadotrophin
hCG

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: hCG with rFSH during puberty was followed by fertility in six men with congenital hypogonadotropic hypogonadism standing
- resolved
Fertility outcomes in male adults with congenital hypogonadotropic hypogonadism treated during puberty with human chorionic gonadotropin and recombinant follicle stimulating hormone.
Grob F, Keshwani R, Angley E, Zacharin M
pmid 38572627
- preclinical
  Claim: Crystal structure of hCG: two cystine-knot subunits held by a beta-subunit seat belt standing
- resolved
Crystal structure of human chorionic gonadotropin.
Lapthorn AJ, Harris DC, Littlejohn A, Lustbader JW, Canfield RE, Machin KJ, Morgan FJ, Isaacs NW
pmid 8202136

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Negative findings

failure is information

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