In anemic patients with non-dialysis chronic kidney disease, 1 g of intravenous iron sucrose raised hemoglobin by at least 1 g/dL in more patients than oral ferrous sulfate (44.3% against 28.0%).
established — replicated in humans, or settled by a regulator
every claim resolves to its source
All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.
Summary
In anemic patients with non-dialysis chronic kidney disease, 1 g of intravenous iron sucrose raised hemoglobin by at least 1 g/dL in more patients than oral ferrous sulfate (44.3% against 28.0%). · pmid:16316362
In the FERRIC-HF trial in 35 patients with chronic heart failure and iron deficiency, intravenous iron sucrose improved peak oxygen consumption per kilogram and NYHA class against no treatment. · pmid:18191732
Identity
No public registry record is shown for this page: PubChem gave no record that proves it is this substance.
Where the evidence actually sits
Established50%
Emerging50%
Proportion of the 2 claims about Iron sucrose standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.
Living evidence history
2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.
Structure
No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Iron sucrose yet.
Dose evidence, rung by rung
A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.
Approved-label dose· a resolved regulatory document names a labelled dose
nothing resolved on this rung
Studied human doses· resolved human studies at the established tier
A randomized, controlled trial comparing IV iron sucrose to oral iron in anemic patients with nondialysis-dependent CKD. · pmid 16316362 · 2005
Observational evidence· resolved human data at the emerging tier: thin, or contested
Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: a randomized, controlled, observer-blinded trial. · pmid 18191732 · 2008
Community-reported protocols· protocol propositions from distinct members, counted once per human
nothing resolved on this rung
Preclinical evidence· resolved animal, cell or mechanistic work
nothing resolved on this rung
2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.
Negative findings
failure is information
Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.