established — replicated in humans, or settled by a regulator
every claim resolves to its source
All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.
Summary
Liraglutide is a glucagon-like peptide-1 analogue given by once-daily subcutaneous injection. · pmid:26132939
History
In the LEADER trial of 9,340 people with type 2 diabetes and high cardiovascular risk, fewer patients on liraglutide than on placebo had cardiovascular death, non-fatal heart attack or non-fatal stroke (13.0% against 14.9%; hazard ratio 0.87). · pmid:27295427
A 56-week trial in 3,731 people with obesity and no diabetes studied the 3.0 mg daily dose alongside lifestyle counselling for weight management. · pmid:26132939
Proportion of the 2 claims about Liraglutide standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.
Living evidence history
2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.
Structure
No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Liraglutide yet.
Dose evidence, rung by rung
A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.
Approved-label dose· a resolved regulatory document names a labelled dose
nothing resolved on this rung
Studied human doses· resolved human studies at the established tier
A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. · pmid 26132939 · 2015
Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes. · pmid 27295427 · 2016
Observational evidence· resolved human data at the emerging tier: thin, or contested
nothing resolved on this rung
Community-reported protocols· protocol propositions from distinct members, counted once per human
nothing resolved on this rung
Preclinical evidence· resolved animal, cell or mechanistic work
nothing resolved on this rung
2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.
Negative findings
failure is information
Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.