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Peptide Atlas · Peptide

Melanotan I

Afamelanotide is an analogue of alpha-melanocyte-stimulating hormone, studied as a subcutaneous implant.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

    • emerging
      Claim: Long-term observational study in 115 patients standing
    • resolved

    Long-term observational study of afamelanotide in 115 patients with erythropoietic protoporphyria.

    Biolcati G, Marchesini E, Sorge F, Barbieri L, Schneider-Yin X, Minder EI

    pmid 25494545

    • established
      Claim: Two randomized trials of afamelanotide in erythropoietic protoporphyria standing
    • resolved

    Afamelanotide for Erythropoietic Protoporphyria.

    Langendonk JG, Balwani M, Anderson KE, Bonkovsky HL, Anstey AV, Bissell DM, Bloomer J, Edwards C, Neumann NJ, Parker C, Phillips JD, Lim HW, Hamzavi I, Deybach JC, Kauppinen R, Rhodes LE, Frank J, Murphy GM, Karstens FPJ, Sijbrands EJG, de Rooij FWM, Lebwohl M, Naik H, Goding CR, Wilson JHP, Desnick RJ

    pmid 26132941

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.