Peptide Atlas · Cofactor

NADH (Nicotinamide adenine dinucleotide, reduced)

In a randomized, double-blind crossover pilot study in 26 people with chronic fatigue syndrome, 8 responded to a stabilized oral form of NADH (the reduced form of nicotinamide adenine dinucleotide) against 2 on placebo.

emerging

provisional
PubChem 439153
2 citations
0 discussions
0 followers
Coenzyme I reduced
DPNH
beta-NADH
dihydronicotinamide adenine dinucleotide
reduced NAD

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

created page created as 'NADH (Nicotinamide adenine dinucleotide, reduced)' with aliases beta-NADH, reduced NAD, dihydronicotinamide adenine dinucleotide, DPNH, Coenzyme I reduced · 2026-09-27 12:04 · somebody
kind set kind set to cofactor: palette r2 · 2026-09-27 12:04 · somebody
fact added identity: PubChem CID 439153: Nadh, C21H29N7O14P2, 665.4 g/mol. · 2026-09-27 12:04 · somebody
fact added identity: CAS registry number 58-68-4. · 2026-09-27 12:04 · somebody
fact added identity: IUPAC name: [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-( · 2026-09-27 12:04 · somebody
fact added summary: In a randomized, double-blind crossover pilot study in 26 people with chronic fatigue syndrome, 8 responded to a stabili · 2026-09-27 12:04 · somebody
fact added mechanism: In mice, NADH given by mouth, unlike nicotinamide or NAD+, did not raise urinary nicotinamide metabolites, and NADH was · 2026-09-27 12:04 · somebody
citation added pmid 10071523 cited as emerging: Oral NADH in chronic fatigue syndrome: 8/26 responders versus 2/26 on placebo (pilot crossover RCT) · 2026-09-27 12:04 · somebody
citation added pmid 16802695 cited as preclinical: Oral NADH is degraded before it can supply nicotinamide in mice · 2026-09-27 12:04 · somebody

Negative findings

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