Peptide Atlas · Peptide

Nafarelin

Nafarelin is a GnRH agonist given as a nasal spray; in a six-month double-blind trial in 213 women with endometriosis it reduced disease extent at laparoscopy as much as oral danazol, with hot flashes rather than the adverse lipid changes seen with danazol.

established

provisional
PubChem 25077405
1 citation
0 discussions
0 followers
D-Nal(2)6-LHRH
Nafarelin acetate
Synarel

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Nafarelin. Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Nasal nafarelin was as effective as danazol for endometriosis (double-blind RCT)	established	pmid 2963213

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.