Peptide Atlas · Peptide

Nafarelin

Nafarelin is a GnRH agonist given as a nasal spray; in a six-month double-blind trial in 213 women with endometriosis it reduced disease extent at laparoscopy as much as oral danazol, with hot flashes rather than the adverse lipid changes seen with danazol.

established

provisional
PubChem 25077405
1 citation
0 discussions
0 followers
D-Nal(2)6-LHRH
Nafarelin acetate
Synarel

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

- established
  Claim: Nasal nafarelin was as effective as danazol for endometriosis (double-blind RCT) standing
- resolved
Administration of nasal nafarelin as compared with oral danazol for endometriosis. A multicenter double-blind comparative clinical trial.
Henzl MR, Corson SL, Moghissi K, Buttram VC, Berqvist C, Jacobson J
pmid 2963213

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

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