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P21

P021 is a small neurotrophic and neurogenic peptide mimetic compound, developed to avoid the blood-brain barrier impermeability, short half-life and side effects that halted trials of whole neurotrophic factor proteins in Alzheimer's disease.

What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

    • preclinical
      Claim: Review of pre-clinical studies of the neurotrophic peptide mimetic P021 standing
    • resolved

    Alzheimer's Disease: Challenges and a Therapeutic Opportunity to Treat It with a Neurotrophic Compound.

    Baazaoui N, Iqbal K

    pmid 36291618

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.