Riboflavin-5'-phosphate sodium

Summary

In corneal cross-linking, a riboflavin-saturated cornea of at least 400 micrometres thickness keeps the ultraviolet-A light reaching the endothelium below its damage threshold. · pmid:17457183

Mechanism

Riboflavin 5'-phosphate is flavin mononucleotide (FMN), a coenzyme form of vitamin B2; in bacteria, FMN riboswitches bind it to control genes for riboflavin synthesis and transport. · pmid:19169240

Identity

PubChem CID 23666409: Riboflavin sodium phosphate, C17H20N4NaO9P, 478.3 g/mol. · pubchem:23666409

CAS registry number 130-40-5. · pubchem:23666409

IUPAC name: sodium [(2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate. · pubchem:23666409

Where the evidence actually sits

Proportion of the 2 claims about Riboflavin-5'-phosphate sodium standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.

Living evidence history

2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.

Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Riboflavin-5'-phosphate sodium yet.

Dose evidence, rung by rung

No established safe human dose. Nothing on file establishes one. That is a statement about the evidence PepJunkie holds, not a promise about the molecule.

1. Approved-label dose · a resolved regulatory document names a labelled dose

   nothing resolved on this rung

2. Studied human doses · resolved human studies at the established tier

   nothing resolved on this rung

3. Observational evidence · resolved human data at the emerging tier: thin, or contested
   • Safety of UVA-riboflavin cross-linking of the cornea. · pmid 17457183 · 2007
4. Community-reported protocols · protocol propositions from distinct members, counted once per human

   nothing resolved on this rung

5. Preclinical evidence · resolved animal, cell or mechanistic work
   • Coenzyme recognition and gene regulation by a flavin mononucleotide riboswitch. · pmid 19169240 · 2009

2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.