PepJunkie Home of the Peptonauts
More

Peptide Atlas · Excipient

Sodium Acetate Trihydrate

Sodium acetate is one of the buffers whose pH shifts during freeze-drying were compared with histidine-HCl and histidine-acetate in antibody formulations.

What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

Summary

Sodium acetate is one of the buffers whose pH shifts during freeze-drying were compared with histidine-HCl and histidine-acetate in antibody formulations. · pmid:41308842

Identity

PubChem CID 23665404: Sodium Acetate Trihydrate, C2H9NaO5, 136.08 g/mol. · pubchem:23665404

CAS registry number 6131-90-4. · pubchem:23665404

IUPAC name: sodium;acetate;trihydrate. · pubchem:23665404


Where the evidence actually sits

Preclinical only100%

Proportion of the 1 claim about Sodium Acetate Trihydrate standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.


Living evidence history

A novel histidine-acetate buffer for freeze-dried monoclonal antibody formulations. (2026) · preclinical20262026

1 resolved citation, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.


Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Sodium Acetate Trihydrate yet.


Dose evidence, rung by rung

No established safe human dose. Nothing on file establishes one. That is a statement about the evidence PepJunkie holds, not a promise about the molecule.

  1. Approved-label dose · a resolved regulatory document names a labelled dose

    nothing resolved on this rung

  2. Studied human doses · resolved human studies at the established tier

    nothing resolved on this rung

  3. Observational evidence · resolved human data at the emerging tier: thin, or contested

    nothing resolved on this rung

  4. Community-reported protocols · protocol propositions from distinct members, counted once per human

    nothing resolved on this rung

  5. Preclinical evidence · resolved animal, cell or mechanistic work
    • A novel histidine-acetate buffer for freeze-dried monoclonal antibody formulations. · pmid 41308842 · 2026

1 resolved citation, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.