In a double-blind, placebo-controlled study in 2,534 hemodialysis patients, sodium ferric gluconate complex given without a test dose caused drug intolerance in 0.44%, far below a historical iron dextran control (2.47%).
established
provisional
2 citations
0 discussions
0 followers
Ferrlecit
ferric gluconate
sodium ferric gluconate complex in sucrose injection
established — replicated in humans, or settled by a regulator
every claim resolves to its source
All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.
Summary
In a double-blind, placebo-controlled study in 2,534 hemodialysis patients, sodium ferric gluconate complex given without a test dose caused drug intolerance in 0.44%, far below a historical iron dextran control (2.47%). · pmid:11967034
Sodium ferric gluconate complex in sucrose has been used since 1959, mainly in Europe; spontaneous reports showed a lower allergy reporting rate than iron dextran and no deaths from 1976 to 1996. · pmid:10070910
Identity
No public registry record is shown for this page: PubChem gave no record that proves it is this substance.
Where the evidence actually sits
Established50%
Emerging50%
Proportion of the 2 claims about Sodium ferric gluconate complex standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.
Living evidence history
2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.
Structure
No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Sodium ferric gluconate complex yet.
Dose evidence, rung by rung
A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.
Approved-label dose· a resolved regulatory document names a labelled dose
nothing resolved on this rung
Studied human doses· resolved human studies at the established tier
Sodium ferric gluconate complex in hemodialysis patients: adverse reactions compared to placebo and iron dextran. · pmid 11967034 · 2002
Observational evidence· resolved human data at the emerging tier: thin, or contested
Sodium ferric gluconate complex in sucrose: safer intravenous iron therapy than iron dextrans. · pmid 10070910 · 1999
Community-reported protocols· protocol propositions from distinct members, counted once per human
nothing resolved on this rung
Preclinical evidence· resolved animal, cell or mechanistic work
nothing resolved on this rung
2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.
Negative findings
failure is information
Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.