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Peptide Atlas · Mineral

Sodium fluoride (injectable)

In a randomized, double-blind trial in 84 postmenopausal women with spinal osteoporosis, oral sodium fluoride was no more effective than placebo and caused more gastrointestinal and lower-limb pain side effects.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

    • emerging
      Claim: 18F-sodium fluoride PET/CT imaging of arterial mineral deposition standing
    • resolved

    Feasibility of 18F-sodium fluoride PET/CT for imaging of atherosclerotic plaque.

    Derlin T, Richter U, Bannas P, Begemann P, Buchert R, Mester J, Klutmann S

    pmid 20484438

    • established
      Claim: Sodium fluoride did not slow spinal osteoporosis versus placebo (RCT, n=84) standing
    • resolved

    A randomized trial of sodium fluoride as a treatment for postmenopausal osteoporosis.

    Kleerekoper M, Peterson EL, Nelson DA, Phillips E, Schork MA, Tilley BC, Parfitt AM

    pmid 1790403

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.