Peptide Atlas · Mineral

Sodium selenite

In the SISPCT trial of 1,089 patients with severe sepsis or septic shock, high-dose intravenous sodium selenite did not lower 28-day mortality (28.3% against 25.5% on placebo).

established

provisional
PubChem 24934
3 citations
0 discussions
0 followers
Na2SeO3
disodium selenite
selenious acid disodium salt
sodium selenite anhydrous

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 3 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Sodium selenite. Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Sodium selenite in severe SIRS, sepsis and septic shock (SIC RCT, n=238)	emerging	pmid 17095947
Phase I pharmacokinetics and toxicity of intravenous sodium selenite in cancer (SECAR)	emerging	pmid 26102212
High-dose sodium selenite did not reduce sepsis mortality (SISPCT RCT, n=1089)	established	pmid 27428731

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.