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Survodutide

Survodutide is a dual glucagon and GLP-1 receptor agonist; in a 48-week phase 2 trial in 293 adults with biopsy-confirmed MASH and fibrosis, MASH improved without fibrosis worsening in 43% to 62% on survodutide against 14% on placebo.

What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Survodutide. Tier reflects study design, not enthusiasm.
ClaimTierSource
Survodutide improved MASH histology in a 48-week phase 2 trialemergingpmid 38847460

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.