established — replicated in humans, or settled by a regulator
every claim resolves to its source
All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.
Summary
Tesamorelin is a growth hormone-releasing factor analogue based on the full GHRH(1-44) sequence. · pmid:20554713
History
A pooled analysis of two phase 3 trials in 806 HIV patients on antiretroviral therapy with excess abdominal fat found visceral fat reduced after 26 weeks of daily tesamorelin compared with placebo. · pmid:20554713
Proportion of the 1 claim about Tesamorelin standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.
Living evidence history
1 resolved citation, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.
Structure
No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Tesamorelin yet.
Dose evidence, rung by rung
A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.
Approved-label dose· a resolved regulatory document names a labelled dose
nothing resolved on this rung
Studied human doses· resolved human studies at the established tier
Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data. · pmid 20554713 · 2010
Observational evidence· resolved human data at the emerging tier: thin, or contested
nothing resolved on this rung
Community-reported protocols· protocol propositions from distinct members, counted once per human
nothing resolved on this rung
Preclinical evidence· resolved animal, cell or mechanistic work
nothing resolved on this rung
1 resolved citation, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.
Negative findings
failure is information
Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.