Triptorelin is a gonadotropin-releasing hormone analogue; in 66 children treated with slow-release triptorelin for central precocious puberty, final height matched the genetic target, and girls gained 4.8 cm over their predicted height.
established — replicated in humans, or settled by a regulator
every claim resolves to its source
All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.
Summary
Triptorelin is a gonadotropin-releasing hormone analogue; in 66 children treated with slow-release triptorelin for central precocious puberty, final height matched the genetic target, and girls gained 4.8 cm over their predicted height. · pmid:10372696
Classification
Triptorelin has been tested as temporary ovarian suppression during chemotherapy to prevent early menopause in premenopausal women with breast cancer (the PROMISE-GIM6 phase 3 trial). · pmid:21771987
Proportion of the 2 claims about Triptorelin standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.
Living evidence history
2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.
Structure
No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Triptorelin yet.
Dose evidence, rung by rung
A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.
Approved-label dose· a resolved regulatory document names a labelled dose
nothing resolved on this rung
Studied human doses· resolved human studies at the established tier
Effect of the gonadotropin-releasing hormone analogue triptorelin on the occurrence of chemotherapy-induced early menopause in premenopausal women with breast cancer: a randomized trial. · pmid 21771987 · 2011
Observational evidence· resolved human data at the emerging tier: thin, or contested
Final height after long-term treatment with triptorelin slow release for central precocious puberty: importance of statural growth after interruption of treatment. French study group of Decapeptyl in Precocious Puberty. · pmid 10372696 · 1999
Community-reported protocols· protocol propositions from distinct members, counted once per human
nothing resolved on this rung
Preclinical evidence· resolved animal, cell or mechanistic work
nothing resolved on this rung
2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.
Negative findings
failure is information
Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.