Peptide Atlas · Buffer system

Tris buffer

Tris buffer degraded in a peptide formulation held at 70 C, liberating formaldehyde that reacted with a tyrosine residue of the peptide.

preclinical

provisional
1 citation
0 discussions
0 followers

Follow this molecule Ask the Hunter-Gatherer

What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

- preclinical
  Claim: Formaldehyde production by Tris buffer in peptide formulations standing
- resolved
Formaldehyde production by Tris buffer in peptide formulations at elevated temperature.
Song Y, Schowen RL, Borchardt RT, Topp EM
pmid 11536224

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.