Research
Adipotide — living evidence map
The Atlas page holds the claims; this is how its evidence evolved.
Summary
Adipotide is the ligand-directed peptidomimetic CKGGRAKDC-GG-(D)(KLAKLAK)2, studied for inducing targeted apoptosis within the blood vessels of white adipose tissue. · pmid:22072637
History
In obese Old World monkeys it caused rapid weight loss and improved insulin resistance, with predictable and reversible changes in renal proximal tubule function at the doses found optimal. · pmid:22072637
Identity
No public registry record is shown for this page: PubChem gave no record that proves it is this substance.
Where the evidence actually sits
Proportion of the 1 claim about Adipotide standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.
Living evidence history
1 resolved citation, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.
Structure
No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Adipotide yet.
Dose evidence, rung by rung
No established safe human dose. Nothing on file establishes one. That is a statement about the evidence PepJunkie holds, not a promise about the molecule.
- Approved-label dose · a resolved regulatory document names a labelled dose
nothing resolved on this rung
- Studied human doses · resolved human studies at the established tier
nothing resolved on this rung
- Observational evidence · resolved human data at the emerging tier: thin, or contested
nothing resolved on this rung
- Community-reported protocols · protocol propositions from distinct members, counted once per human
nothing resolved on this rung
- Preclinical evidence · resolved animal, cell or mechanistic work
- A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys. · pmid 22072637 · 2011
1 resolved citation, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.