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Research

Iron sucrose — living evidence map

The Atlas page holds the claims; this is how its evidence evolved.

Summary

In anemic patients with non-dialysis chronic kidney disease, 1 g of intravenous iron sucrose raised hemoglobin by at least 1 g/dL in more patients than oral ferrous sulfate (44.3% against 28.0%). · pmid:16316362

In the FERRIC-HF trial in 35 patients with chronic heart failure and iron deficiency, intravenous iron sucrose improved peak oxygen consumption per kilogram and NYHA class against no treatment. · pmid:18191732

Identity

No public registry record is shown for this page: PubChem gave no record that proves it is this substance.

Where the evidence actually sits

Established50%
Emerging50%

Proportion of the 2 claims about Iron sucrose standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.

Living evidence history

A randomized, controlled trial comparing IV iron sucrose to oral iron in anemic patients with nondialysis-dependent CKD. (2005) · establishedEffect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: a randomized, controlled, observer-blinded trial. (2008) · emerging20052008

2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.

Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Iron sucrose yet.

Dose evidence, rung by rung

A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.

  1. Approved-label dose · a resolved regulatory document names a labelled dose

    nothing resolved on this rung

  2. Studied human doses · resolved human studies at the established tier
    • A randomized, controlled trial comparing IV iron sucrose to oral iron in anemic patients with nondialysis-dependent CKD. · pmid 16316362 · 2005
  3. Observational evidence · resolved human data at the emerging tier: thin, or contested
    • Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: a randomized, controlled, observer-blinded trial. · pmid 18191732 · 2008
  4. Community-reported protocols · protocol propositions from distinct members, counted once per human

    nothing resolved on this rung

  5. Preclinical evidence · resolved animal, cell or mechanistic work

    nothing resolved on this rung

2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.