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Research

Manganese sulfate (mono/tetrahydrate) — living evidence map

The Atlas page holds the claims; this is how its evidence evolved.

Summary

Manganese is an essential mineral present in almost all diets; the body keeps tissue levels stable by controlling both absorption and excretion, while excess accumulation in the brain causes manganism, a condition resembling Parkinson's disease. · pmid:16099026

Manganese is required by enzymes such as arginase and glutamine synthetase, and growing evidence links its handling to Parkinson's and Huntington's disease. · pmid:25974698

Identity

PubChem CID 177577: Manganese sulfate monohydrate, H2MnO5S, 169.02 g/mol. · pubchem:177577

CAS registry number 10034-96-5. · pubchem:177577

IUPAC name: manganese(2+);sulfate;hydrate. · pubchem:177577

Where the evidence actually sits

Established100%

Proportion of the 2 claims about Manganese sulfate (mono/tetrahydrate) standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.

Living evidence history

Nutritional aspects of manganese homeostasis. (2005) · establishedManganese Is Essential for Neuronal Health. (2015) · established20052015

2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.

Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Manganese sulfate (mono/tetrahydrate) yet.

Dose evidence, rung by rung

A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.

  1. Approved-label dose · a resolved regulatory document names a labelled dose

    nothing resolved on this rung

  2. Studied human doses · resolved human studies at the established tier
    • Nutritional aspects of manganese homeostasis. · pmid 16099026 · 2005
    • Manganese Is Essential for Neuronal Health. · pmid 25974698 · 2015
  3. Observational evidence · resolved human data at the emerging tier: thin, or contested

    nothing resolved on this rung

  4. Community-reported protocols · protocol propositions from distinct members, counted once per human

    nothing resolved on this rung

  5. Preclinical evidence · resolved animal, cell or mechanistic work

    nothing resolved on this rung

2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.