Research
MES — living evidence map
The Atlas page holds the claims; this is how its evidence evolved.
Summary
MES is one of the Good's buffers; on freezing these buffers tend to become more basic, and MES showed the largest change of the three studied, up to two pH units. · pmid:33271311
Identity
PubChem CID 78165: 4-Morpholineethanesulfonic acid, C6H13NO4S, 195.24 g/mol. · pubchem:78165
CAS registry number 4432-31-9. · pubchem:78165
IUPAC name: 2-morpholin-4-ylethanesulfonic acid. · pubchem:78165
Where the evidence actually sits
Proportion of the 2 claims about MES standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.
Living evidence history
2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.
Structure
No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for MES yet.
Dose evidence, rung by rung
A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.
- Approved-label dose · a resolved regulatory document names a labelled dose
nothing resolved on this rung
- Studied human doses · resolved human studies at the established tier
- Hydrogen ion buffers for biological research. · pmid 5942950 · 1966
- Observational evidence · resolved human data at the emerging tier: thin, or contested
nothing resolved on this rung
- Community-reported protocols · protocol propositions from distinct members, counted once per human
nothing resolved on this rung
- Preclinical evidence · resolved animal, cell or mechanistic work
- Making good's buffers good for freezing: The acidity changes and their elimination via mixing with sodium phosphate. · pmid 33271311 · 2021
2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.