Oxytocin — living evidence map

Summary

Oxytocin is a neurohypophysial peptide hormone made mainly in the hypothalamic paraventricular and supraoptic nuclei and released from the posterior pituitary in response to stimuli such as suckling and parturition. · pmid:11274341

Mechanism

Its receptor is a class I G protein-coupled receptor coupled mainly through Gq proteins to phospholipase C-beta. · pmid:11274341

Identity

PubChem CID 439302: Oxytocin, C43H66N12O12S2, 1007.2 g/mol. · pubchem:439302

CAS registry number 50-56-6. · pubchem:439302

Where the evidence actually sits

Proportion of the 1 claim about Oxytocin standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.

Living evidence history

1 resolved citation, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.

Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Oxytocin yet.

Dose evidence, rung by rung

A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.

1. Approved-label dose · a resolved regulatory document names a labelled dose

   nothing resolved on this rung

2. Studied human doses · resolved human studies at the established tier
   • The oxytocin receptor system: structure, function, and regulation. · pmid 11274341 · 2001
3. Observational evidence · resolved human data at the emerging tier: thin, or contested

   nothing resolved on this rung

4. Community-reported protocols · protocol propositions from distinct members, counted once per human

   nothing resolved on this rung

5. Preclinical evidence · resolved animal, cell or mechanistic work

   nothing resolved on this rung

1 resolved citation, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.