PepJunkie Home of the Peptonauts
More
HomeThe PulseAtlasDiscussHunter-GathererResearchProfileSearch

Research

Sodium ascorbate (Vitamin C salt) — living evidence map

The Atlas page holds the claims; this is how its evidence evolved.

Summary

A survey of US complementary-medicine practitioners found high-dose intravenous vitamin C given to thousands of patients a year, mostly with minor side effects; serious events, including two deaths, were published in patients with known risks such as kidney impairment or G6PD deficiency. · pmid:20628650

Mechanism

Only intravenous vitamin C reaches high plasma concentrations: 1.25 g gave peak levels of about 885 micromol/L intravenously against about 135 micromol/L by mouth. · pmid:15068981

Identity

PubChem CID 23667548: Sodium Ascorbate, C6H7NaO6, 198.11 g/mol. · pubchem:23667548

CAS registry number 134-03-2. · pubchem:23667548

IUPAC name: sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2H-furan-3-olate. · pubchem:23667548

Where the evidence actually sits

Established50%
Emerging50%

Proportion of the 2 claims about Sodium ascorbate (Vitamin C salt) standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.

Living evidence history

Vitamin C pharmacokinetics: implications for oral and intravenous use. (2004) · establishedVitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects. (2010) · emerging20042010

2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.

Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Sodium ascorbate (Vitamin C salt) yet.

Dose evidence, rung by rung

A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.

  1. Approved-label dose · a resolved regulatory document names a labelled dose

    nothing resolved on this rung

  2. Studied human doses · resolved human studies at the established tier
    • Vitamin C pharmacokinetics: implications for oral and intravenous use. · pmid 15068981 · 2004
  3. Observational evidence · resolved human data at the emerging tier: thin, or contested
    • Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects. · pmid 20628650 · 2010
  4. Community-reported protocols · protocol propositions from distinct members, counted once per human

    nothing resolved on this rung

  5. Preclinical evidence · resolved animal, cell or mechanistic work

    nothing resolved on this rung

2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.