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Sodium Bicarbonate — living evidence map

The Atlas page holds the claims; this is how its evidence evolved.

Summary

Sodium bicarbonate is used to raise the pH of acidic local anaesthetic solutions; adding it to lidocaine reduced infiltration pain in a randomized study of 100 patients. · pmid:2174653

Identity

PubChem CID 516892: Sodium Bicarbonate, CHNaO3, 84.007 g/mol. · pubchem:516892

CAS registry number 144-55-8. · pubchem:516892

IUPAC name: sodium hydrogen carbonate. · pubchem:516892


Where the evidence actually sits

Established100%

Proportion of the 1 claim about Sodium Bicarbonate standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.


Living evidence history

pH-adjustment and discomfort caused by the intradermal injection of lignocaine. (1990) · established19901990

1 resolved citation, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.


Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Sodium Bicarbonate yet.


Dose evidence, rung by rung

A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.

  1. Approved-label dose · a resolved regulatory document names a labelled dose

    nothing resolved on this rung

  2. Studied human doses · resolved human studies at the established tier
    • pH-adjustment and discomfort caused by the intradermal injection of lignocaine. · pmid 2174653 · 1990
  3. Observational evidence · resolved human data at the emerging tier: thin, or contested

    nothing resolved on this rung

  4. Community-reported protocols · protocol propositions from distinct members, counted once per human

    nothing resolved on this rung

  5. Preclinical evidence · resolved animal, cell or mechanistic work

    nothing resolved on this rung

1 resolved citation, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.