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Research

Sodium fluoride (injectable) — living evidence map

The Atlas page holds the claims; this is how its evidence evolved.

Summary

In a randomized, double-blind trial in 84 postmenopausal women with spinal osteoporosis, oral sodium fluoride was no more effective than placebo and caused more gastrointestinal and lower-limb pain side effects. · pmid:1790403

Fluorine-18-labelled sodium fluoride is used in PET/CT to image mineral deposition, including in calcified arterial plaque. · pmid:20484438

Identity

PubChem CID 5235: Sodium Fluoride, FNa, 41.9881724 g/mol. · pubchem:5235

CAS registry number 7681-49-4. · pubchem:5235

IUPAC name: sodium fluoride. · pubchem:5235

Where the evidence actually sits

Established50%
Emerging50%

Proportion of the 2 claims about Sodium fluoride (injectable) standing at each tier. Community volume is shown on the Consensus tab beside this and is never averaged into it.

Living evidence history

A randomized trial of sodium fluoride as a treatment for postmenopausal osteoporosis. (1991) · establishedFeasibility of 18F-sodium fluoride PET/CT for imaging of atherosclerotic plaque. (2010) · emerging19912010

2 resolved citations, oldest to newest, coloured by tier. Retractions and contradictions land here as they are recorded.

Structure

No structure representation on record. PepJunkie draws only what an authoritative record supplies; for a peptide that is the residue sequence, and none has been curated for Sodium fluoride (injectable) yet.

Dose evidence, rung by rung

A studied human dose exists on file. Open the rung: the dose is the paper's, in its context, never PepJunkie's.

  1. Approved-label dose · a resolved regulatory document names a labelled dose

    nothing resolved on this rung

  2. Studied human doses · resolved human studies at the established tier
    • A randomized trial of sodium fluoride as a treatment for postmenopausal osteoporosis. · pmid 1790403 · 1991
  3. Observational evidence · resolved human data at the emerging tier: thin, or contested
    • Feasibility of 18F-sodium fluoride PET/CT for imaging of atherosclerotic plaque. · pmid 20484438 · 2010
  4. Community-reported protocols · protocol propositions from distinct members, counted once per human

    nothing resolved on this rung

  5. Preclinical evidence · resolved animal, cell or mechanistic work

    nothing resolved on this rung

2 resolved citations, 0 unresolved (an unresolved citation lends nothing). Community volume is its own rung and is never averaged into the evidence rungs.