Peptide Atlas · Peptide

ACE-031

ACE-031 is a fusion protein of the activin receptor type IIB and an IgG1 Fc domain that binds myostatin and related ligands that restrain muscle growth.

emerging

provisional
2 citations
0 discussions
0 followers
ACVR2B-Fc
Activin Receptor Type IIB-Fc
Ramatercept

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for ACE-031. Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Single ascending-dose study in healthy volunteers: increases in lean mass and thigh muscle volume	emerging	pmid 23169607
Randomized trial in Duchenne muscular dystrophy stopped over epistaxis and telangiectasias	emerging	pmid 27462804

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.