ACE-031 is a fusion protein of the activin receptor type IIB and an IgG1 Fc domain that binds myostatin and related ligands that restrain muscle growth.
emerging — human data exists, and it is thin or contested
every claim resolves to its source
All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.
created page created as 'ACE-031' with aliases Ramatercept, ACVR2B-Fc, Activin Receptor Type IIB-Fc · 2026-09-27 04:00 · somebody
kind set kind set to peptide: palette r1 · 2026-09-27 04:00 · somebody
identity withheld identity not published: PubChem gave no record that proves it is this substance · 2026-09-27 04:00 · somebody
fact added summary: ACE-031 is a fusion protein of the activin receptor type IIB and an IgG1 Fc domain that binds myostatin and related liga · 2026-09-27 04:00 · somebody
fact added history: In 48 healthy postmenopausal women, a single dose at the highest level tested raised total lean mass by 3.3% and thigh m · 2026-09-27 04:00 · somebody
fact added history: A randomized trial in boys with Duchenne muscular dystrophy was stopped after its second dosing regimen because of epist · 2026-09-27 04:00 · somebody
citation added pmid 23169607 cited as emerging: Single ascending-dose study in healthy volunteers: increases in lean mass and thigh muscle volume · 2026-09-27 04:00 · somebody
citation added pmid 27462804 cited as emerging: Randomized trial in Duchenne muscular dystrophy stopped over epistaxis and telangiectasias · 2026-09-27 04:00 · somebody
Negative findings
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