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Peptide Atlas · Small molecule

Acetyl-L-Carnitine (ALCAR)

A meta-analysis of double-blind, placebo-controlled trials lasting 3 to 12 months in mild cognitive impairment and mild Alzheimer's disease found a small advantage for acetyl-L-carnitine over placebo on clinical and psychometric measures.

What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

  • created page created as 'Acetyl-L-Carnitine (ALCAR)' with aliases ALCAR, ALC, O-acetyl-L-carnitine, levacecarnine, acetylcarnitine · 2026-09-27 12:04 · somebody
  • kind set kind set to small_molecule: palette r2 · 2026-09-27 12:04 · somebody
  • fact added identity: PubChem CID 7045767: Acetyl-L-Carnitine, C9H17NO4, 203.24 g/mol. · 2026-09-27 12:04 · somebody
  • fact added identity: CAS registry number 3040-38-8. · 2026-09-27 12:04 · somebody
  • fact added identity: IUPAC name: (3R)-3-acetyloxy-4-(trimethylazaniumyl)butanoate. · 2026-09-27 12:04 · somebody
  • fact added summary: A meta-analysis of double-blind, placebo-controlled trials lasting 3 to 12 months in mild cognitive impairment and mild · 2026-09-27 12:04 · somebody
  • fact added summary: In a 24-week randomized trial in 409 women receiving taxane chemotherapy for breast cancer, acetyl-L-carnitine did not p · 2026-09-27 12:04 · somebody
  • citation added pmid 12598816 cited as emerging: Meta-analysis: small effect of acetyl-L-carnitine over placebo in MCI and mild Alzheimer's disease · 2026-09-27 12:04 · somebody
  • citation added pmid 23733756 cited as emerging: Acetyl-L-carnitine increased taxane-induced neuropathy at 24 weeks in a placebo-controlled trial · 2026-09-27 12:04 · somebody

Negative findings

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