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Peptide Atlas · Vitamin

Biotin

In a randomized, double-blind trial in 154 people with progressive multiple sclerosis, high-dose biotin (MD1003, 100 mg three times daily) reversed disability in 12.6% against none on placebo.

What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

  • kind set kind set to vitamin: palette r2 · 2026-09-27 12:04 · somebody
  • fact added identity: PubChem CID 171548: Biotin, C10H16N2O3S, 244.31 g/mol. · 2026-09-27 12:04 · somebody
  • created page created as 'Biotin' with aliases Vitamin B7, Vitamin H, D-Biotin, Coenzyme R · 2026-09-27 12:04 · somebody
  • fact added identity: CAS registry number 58-85-5. · 2026-09-27 12:04 · somebody
  • fact added identity: IUPAC name: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid. · 2026-09-27 12:04 · somebody
  • fact added summary: In a randomized, double-blind trial in 154 people with progressive multiple sclerosis, high-dose biotin (MD1003, 100 mg · 2026-09-27 12:04 · somebody
  • citation added pmid 27589059 cited as emerging: High-dose biotin reversed disability in a subset with progressive MS (RCT, n=154) · 2026-09-27 12:04 · somebody
  • question added High biotin intake is reported to interfere with laboratory immunoassays; which tests are affected, and at what doses? · 2026-09-27 12:04 · somebody

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.