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Peptide Atlas · Vitamin

Biotin

In a randomized, double-blind trial in 154 people with progressive multiple sclerosis, high-dose biotin (MD1003, 100 mg three times daily) reversed disability in 12.6% against none on placebo.

What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

    • emerging
      Claim: High-dose biotin reversed disability in a subset with progressive MS (RCT, n=154) standing
    • resolved

    MD1003 (high-dose biotin) for the treatment of progressive multiple sclerosis: A randomised, double-blind, placebo-controlled study.

    Tourbah A, Lebrun-Frenay C, Edan G, Clanet M, Papeix C, Vukusic S, De Sèze J, Debouverie M, Gout O, Clavelou P, Defer G, Laplaud DA, Moreau T, Labauge P, Brochet B, Sedel F, Pelletier J, MS-SPI study group

    pmid 27589059

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.