Cetrorelix is a decapeptide GnRH (LHRH) antagonist: unlike agonists it suppresses LH and FSH at once, without an initial surge, by competitive receptor blockade; after phase III trials in IVF it became the first LHRH antagonist approved for clinical use.
fact added identity: CAS registry number 120287-85-6, 130143-01-0. · 2026-09-27 12:04 · somebody
fact added summary: Cetrorelix is a decapeptide GnRH (LHRH) antagonist: unlike agonists it suppresses LH and FSH at once, without an initial · 2026-09-27 12:04 · somebody
fact added summary: In 65 women undergoing ovarian stimulation for IVF, a single 3 mg or 2 mg injection of cetrorelix prevented LH surges fo · 2026-09-27 12:04 · somebody
citation added pmid 10972520 cited as established: Review: cetrorelix, the first clinically approved LHRH antagonist · 2026-09-27 12:04 · somebody
citation added pmid 9806259 cited as emerging: A single cetrorelix injection prevented LH surges in IVF stimulation · 2026-09-27 12:04 · somebody
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