Peptide Atlas · Peptide

Cetrorelix

Cetrorelix is a decapeptide GnRH (LHRH) antagonist: unlike agonists it suppresses LH and FSH at once, without an initial surge, by competitive receptor blockade; after phase III trials in IVF it became the first LHRH antagonist approved for clinical use.

established

provisional
PubChem 25074887
2 citations
0 discussions
0 followers
Cetrorelix acetate
Cetrotide
GnRH antagonist
SB-75

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: A single cetrorelix injection prevented LH surges in IVF stimulation standing
- resolved
The use of a GnRH antagonist (Cetrorelix) in a single dose protocol in IVF-embryo transfer: a dose finding study of 3 versus 2 mg.
Olivennes F, Alvarez S, Bouchard P, Fanchin R, Salat-Baroux J, Frydman R
pmid 9806259
- established
  Claim: Review: cetrorelix, the first clinically approved LHRH antagonist standing
- resolved
The LHRH antagonist cetrorelix: a review.
Reissmann T, Schally AV, Bouchard P, Riethmiiller H, Engel J
pmid 10972520

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Negative findings

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