Peptide Atlas · Excipient

Citric Acid

Citrate is a common buffer in injectable biologics; a systematic review found that five of seven direct comparisons reported less injection-site pain with citrate-free formulations.

emerging

provisional
PubChem 22230
1 citation
0 discussions
0 followers
Citric acid monohydrate

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

created page created as 'Citric Acid' with aliases Citric acid monohydrate · 2026-09-27 04:00 · somebody
kind set kind set to excipient: palette r1 · 2026-09-27 04:00 · somebody
fact added identity: PubChem CID 22230: 2-Hydroxy-1,2,3-propanetricarboxylic acid hydrate (1:1), C6H10O8, 210.14 g/mol. · 2026-09-27 04:00 · somebody
fact added identity: CAS registry number 5949-29-1. · 2026-09-27 04:00 · somebody
fact added identity: IUPAC name: 2-hydroxypropane-1,2,3-tricarboxylic acid;hydrate. · 2026-09-27 04:00 · somebody
fact added summary: Citrate is a common buffer in injectable biologics; a systematic review found that five of seven direct comparisons repo · 2026-09-27 04:00 · somebody
citation added pmid 36043729 cited as emerging: Systematic review: injection-site pain with citrate-free and citrate-containing biologics · 2026-09-27 04:00 · somebody

Negative findings

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