In a Russian multicenter randomized study in 189 patients with chronic cerebral ischemia, intramuscular cortexin reduced neurological symptoms, asthenia and sleep disturbance in a dose-dependent way compared with basic treatment alone.
emerging — human data exists, and it is thin or contested
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created page created as 'Cortexin' with aliases cortexin polypeptide complex, cerebral cortex polypeptides, bovine/porcine cortex peptide extract · 2026-09-27 12:04 · somebody
kind set kind set to other: palette r2 · 2026-09-27 12:04 · somebody
identity withheld identity not published: PubChem gave no record that proves it is this substance · 2026-09-27 12:04 · somebody
fact added classification: Cortexin is a lyophilised extract of animal cerebral cortex containing neuropeptides, amino acids and trace elements; it · 2026-09-27 12:04 · somebody
fact added mechanism: In rat models of acute and chronic brain ischemia, cortexin improved recovery of neurological function and reduced tissu · 2026-09-27 12:04 · somebody
fact added summary: In a Russian multicenter randomized study in 189 patients with chronic cerebral ischemia, intramuscular cortexin reduced · 2026-09-27 12:04 · somebody
citation added pmid 26356623 cited as preclinical: Review (Russian): composition and proposed targets of cortexin · 2026-09-27 12:04 · somebody
citation added pmid 34260655 cited as preclinical: Cortexin, Cerebrolysin and Actovegin in rat brain ischemia models · 2026-09-27 12:04 · somebody
question added The name cortexin is also used for an unrelated neuronal membrane protein; which peer-reviewed studies of the drug have · 2026-09-27 12:04 · somebody
Negative findings
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