Peptide Atlas · Other substance

Cortexin

In a Russian multicenter randomized study in 189 patients with chronic cerebral ischemia, intramuscular cortexin reduced neurological symptoms, asthenia and sleep disturbance in a dose-dependent way compared with basic treatment alone.

emerging

provisional
3 citations
0 discussions
1 follower
bovine/porcine cortex peptide extract
cerebral cortex polypeptides
cortexin polypeptide complex

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 3 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: Cortexin in chronic cerebral ischemia (Russian multicenter RCT, n=189) standing
- resolved
[Dose-dependent effects of cortexin in chronic cerebral ischemia (results of a multicenter randomized controlled study)].
Fedin AI, Belskaya GN, Kurushina OV, Kovalchuk VV, Starych EV, Chichanovskaya LV, Baranova OA
pmid 30335070
- preclinical
  Claim: Review (Russian): composition and proposed targets of cortexin standing
- resolved
[Cortexin. Molecular mechanisms and targets of neuroprotective activity].
Gomazkov OA
pmid 26356623
- preclinical
  Claim: Cortexin, Cerebrolysin and Actovegin in rat brain ischemia models standing
- resolved
Neuroprotective action of Cortexin, Cerebrolysin and Actovegin in acute or chronic brain ischemia in rats.
Kurkin DV, Bakulin DA, Morkovin EI, Kalatanova AV, Makarenko IE, Dorotenko AR, Kovalev NS, Dubrovina MA, Verkholyak DV, Abrosimova EE, Smirnov AV, Shmidt MV, Tyurenkov IN
pmid 34260655

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Negative findings

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