Peptide Atlas · Peptide

DNSP-11

DNSP-11 (dopamine neuron stimulating peptide-11) is an 11-amino-acid amidated peptide proposed to arise from the proregion of the human GDNF precursor; a single dose into the rat substantia nigra increased potassium-evoked dopamine release in parts of the striatum two weeks later.

preclinical

provisional
2 citations
0 discussions
0 followers
Dopamine Neuron Stimulating Peptide-11

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for DNSP-11. Tier reflects study design, not enthusiasm.
Claim	Tier	Source
DNSP-11 changes dopamine neuron function in rats and phosphorylates ERK1/2 in vitro	preclinical	pmid 24406899
Repeated intranasal DNSP-11 in normal and 6-OHDA-lesioned rats	preclinical	pmid 25999268

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.