Epitalon (Epithalon) is the tetrapeptide Ala-Glu-Asp-Gly (AEDG), synthesized on the basis of the amino acid composition of epithalamin, a bovine pineal gland extract.
fact added summary: Epitalon (Epithalon) is the tetrapeptide Ala-Glu-Asp-Gly (AEDG), synthesized on the basis of the amino acid composition · 2026-09-27 04:00 · somebody
fact added mechanism: Added to telomerase-negative human fetal fibroblasts, it induced expression of the telomerase catalytic subunit, telomer · 2026-09-27 04:00 · somebody
fact added history: Given monthly to female CBA mice from six months of age until natural death, the tetrapeptide increased mean survival by · 2026-09-27 04:00 · somebody
fact added history: A 2025 review notes that physico-chemical and structural studies of the peptide remain limited and that it is uncertain · 2026-09-27 04:00 · somebody
citation added pmid 40141333 cited as preclinical: 2025 overview of epitalon research · 2026-09-27 04:00 · somebody
citation added pmid 12937682 cited as preclinical: Telomerase induction and telomere elongation in human fibroblasts · 2026-09-27 04:00 · somebody
citation added pmid 11163623 cited as preclinical: Survival and tumour incidence in female CBA mice · 2026-09-27 04:00 · somebody
Negative findings
failure is information
Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.