Peptide Atlas · Cofactor

Glutathione disulfide (GSSG, oxidized glutathione)

Glutathione disulfide (GSSG) is the oxidized form of glutathione; the GSSG/glutathione couple is the most abundant redox couple in a cell and serves as an indicator of its redox environment.

established

provisional
PubChem 65359
1 citation
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GSSG
L-glutathione oxidized
glutathione dimer
oxidized glutathione

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

created page created as 'Glutathione disulfide (GSSG, oxidized glutathione)' with aliases GSSG, oxidized glutathione, L-glutathione oxidized, glutathione dimer · 2026-09-27 12:04 · somebody
kind set kind set to cofactor: palette r2 · 2026-09-27 12:04 · somebody
fact added identity: PubChem CID 65359: Glutathione Disulfide, C20H32N6O12S2, 612.6 g/mol. · 2026-09-27 12:04 · somebody
fact added identity: CAS registry number 27025-41-8. · 2026-09-27 12:04 · somebody
fact added identity: IUPAC name: (2S)-2-amino-5-[[(2R)-3-[[(2R)-2-[[(4S)-4-amino-4-carboxybutanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl] · 2026-09-27 12:04 · somebody
fact added summary: Glutathione disulfide (GSSG) is the oxidized form of glutathione; the GSSG/glutathione couple is the most abundant redox · 2026-09-27 12:04 · somebody
fact added mechanism: The half-cell reduction potential of the GSSG/glutathione couple has been estimated at about -240 mV in proliferating ce · 2026-09-27 12:04 · somebody
citation added pmid 11368918 cited as preclinical: The GSSG/2GSH couple as the indicator of a cell's redox environment · 2026-09-27 12:04 · somebody

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