Glycerol is a cosolvent that stabilizes proteins in solution: seven proteins studied in glycerol-water mixtures were preferentially hydrated, which minimizes glycerol contact and favours the native structure.
fact added summary: Glycerol is a cosolvent that stabilizes proteins in solution: seven proteins studied in glycerol-water mixtures were pre · 2026-09-27 04:00 · somebody
fact added mechanism: It shifts proteins toward more compact states and inhibits aggregation during refolding, largely through electrostatic i · 2026-09-27 04:00 · somebody
citation added pmid 7295639 cited as preclinical: Protein stabilization by glycerol through preferential hydration · 2026-09-27 04:00 · somebody
citation added pmid 19817484 cited as preclinical: Mechanisms of protein stabilization and aggregation prevention by glycerol · 2026-09-27 04:00 · somebody
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